The need for good quality sleep is essential for promoting proper healing and maintaining healthy bodily function. Pain, which may be associated with injury and acute and chronic disorders often compromises the body’s ability to heal by leading to sleep disorders. It has been found that the body is regenerative process occurs at night because 70% of growth hormones are produced while sleeping.

Hormones are chemical substances secreted into the blood by the endocrine glands and carried by blood and tissue fluids to the cells they act upon. Different classes of hormones (such as steroid, peptide or protein and amine) act on the target tissue by different mechanisms and can alter the function of the target tissue.

Peptide and protein hormones (insulin) stimulate the intracellular enzyme activity by interacting with receptor sites on the cell surface. Protein is needed to meet the need for tissue repair and resistance to infection. Protein helps to replace losses resulting from immobility. Steroid hormones (such as glucocorticoids and hydrocorticoids) are important factors of glucose metabolism. Increased secretion of these hormones can result in elevated blood glucose levels.

Muscle strains, spasm, injury and fatigue from the effect of extensive exercise and training may disrupt sleeping patterns. The lack of sleep and hormonal instability is not unusual in in athletes.  Sleep deprivation can diminish the body’s ability to secrete and respond to the hormone insulin which helps regulate blood sugar. Athletes can have compromised blood sugar and insulin levels, and further problems with sleeping can lead to poor health and complications.

After injury, muscle healing occurs through different phases, including (1) degeneration and inflammation, (2) muscle regeneration, and (3) development of fibrosis.

The severity and type of muscle injury influence the healing process.

Enhancement of muscle regeneration and prevention of muscle fibrosis can improve muscle healing.

Growth factors, including basic fibroblast growth factor (bFGF), insulin-like growth factor-1 (IGF-1), and nerve growth factor (NGF), can improve muscle regeneration.

The use of the Sport-Z DC stimulation has the effect of transforming growth factor-β1 (TGF-β1) can prevent fibrosis and improve muscle healing, resulting in nearly complete recovery.

Muscle injury presents a challenging problem in traumatology, as injured muscles heal very slowly and often with incomplete functional recovery. It has been observed that injured muscles can initiate regeneration promptly, but the healing process is often inefficient and hindered by the formation of scar tissue, which may contribute to the tendency for muscle injury to recur. The enhancement of muscle regeneration and the prevention of muscle fibrosis through the use of biological DC Stimulation are being investigated in an effort to improve muscle healing after injury.

It is noteworthy to mention that the body naturally minimizes blood flow to the extremities while sleeping to maintain body trunk core temperature and functions. This in turn, can further the process of pain while sleeping. Athletes already suffering from poor circulatory problems in their muscle and vessels may in fact benefit from nighttime therapy that promotes microcirculation.